Natural Stacks CILTEP Review: A Cognitive Performance Booster

Natural Stacks CILTEP Review: A Cognitive Performance Booster

Supported and Endorsed by Celebrities, CILTEP by Natural Stacks is a unique product created by a unique company. 

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Natural Stacks call themselves the first open-source supplement company. Meaning that they openly publish on their website the ingredients and their suppliers.

To me, this is a breath of fresh air after so many companies that like to hide their ingredients behind proprietary blends.

CILTEP has the support of people like Timothy Ferris, who has talked about CILTEP multiple times on his podcast. Dave Osprey, of Bulletproof Coffee fame, has also endorsed CILTEP.

With such heavy hitters in the industry endorsing it, there must be a reason. Let’s take a closer look at the ingredients.

Natural Stacks CILTEP Review: A Cognitive Performance Booster
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Ingredients and Benefits of CILTEP

The CILTEP formula consists only of high quality all-natural ingredients that have been rigorously tested for purity and efficacy.

Artichoke extract (900mg) – Artichoke extract contains Luteolin which works well with Forskolin to provide cognitive benefits such as increasing memory, focus and learning.

Forskolin (20mg) – Forskolin is made from the root of the Indian Coleus plant and is a part of Ayervedic medicine. It is believed to have health benefits such as weight loss, lower blood sugar, reduce inflammation and nerve cell regeneration.

Acetyl-L-Carnitine (750mg) – Acetyl-L-Carnitine (also known as ALCAR) is a form of carnitine, which is involved in the metabolism of food to provide energy, helps support healthy acetylcholine levels in the brain and is an antioxidant.

Vitamin B6 (5mg) – Vitamin B6 plays an essential role in metabolizing food into energy, brain function and healthy hair and skin.

L-Phenylalanine (500mg) – Phenylalanine is an essential amino acid found in meats, fish, eggs, and dairy products and helps to promote balanced neural and cognitive functions, and improves mood.

CILTEP Analysis

The ingredient list to CILTEP is short and sweet, which I like. Some of these manufactured nootropic stacks throw everything and the kitchen sink into their stacks. Natural Stacks went with a very streamlined ingredient list because they have a particular goal for their product.

In fact, their name even states it. CILTEP stands for “chemically induced long-term potentiation.” This idea comes from a 19th century theory of a cellular mechanism believed to be the way to improve memory formation and learning ability.

Natural Stacks’ approach to long-term potentiation (LTP) is through PDE4 inhibition and increasing cAMP.

PDE4 Inhibition

PDE4 is an enzyme that breaks down cAMP molecules. cAMP molecules are used for intracellular signal transduction (passing signals within the cells). By decreasing PDE4, you are indirectly increasing the amount of cAMP in the brain.

Artichoke extract is a natural PDE4 inhibitor.

Increasing cAMP

cAMP (cyclic adenosine monophosphate) is necessary for the regulation of glycogen, sugar, and lipid metabolism. Increased cAMP levels have been shown to lead to increase cognition, improve long term memory, increase wakefulness, and neuroprotection.

Forskolin has been shown to naturally increase cAMP levels.


CILTEP® is a nootropic stack that consists of natural nootropics and was built to help you achieve higher focus, concentration and improved memory.


Natural Stacks CILTEP Overview

I love the transparency of Natural Stacks’ business model. More companies are starting to follow suit and exposing their ingredients list, but hardly any are willing to expose their suppliers as well.

I also love the fact that they use only the highest of quality ingredients in their products. But it is the simplicity of the ingredients in CILTEP that I love the most. The ingredients are focused to achieve long-term potentiation, which it does well. But the simplicity of the ingredients focused on a single goal also makes CILTEP very versatile.

Use CILTEP as a foundation for other stacks. Need a boost of energy in the morning to get you going? Add a caffeine and L-theanine supplement to gain the boost of caffeine without the nervous jitters. Piracetam also stacks well with CILTEP.

While CILTEP doesn’t really show any signs of your body building tolerance to it, I would still recommend a cycle of either weekdays on and weekends off or three weeks on and one week off.

Natural Stacks CILTEP Review: A Cognitive Performance Booster

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