What is Uridine – Uridine is a Cognitive Enhancer
Uridine is one of the five nucleic acids and is produced in the liver as uridine monophosphate (UMP). Uridine is an important component of ribonucleic acid (RNA), one of the two main building blocks found in all life—deoxyribonucleic acid (DNA) being the other.
Uridine is considered a non-essential nutrient as the body does produce what it needs and supplementation is usually not necessary.
Two important sources of uridine are a mother’s milk and beer.
It can also be found in other foods, such as nutritional yeast and brewer’s yeast, cow and pig liver, fish, and vegetables such as mushrooms, broccoli, oats, beets, tomatoes and sugar cane.
An important component of RNA, which is the messenger molecule that delivers DNA, uridine helps with protein synthesis.
Benefits and Effects of Uridine
Certainly, uridine’s role as one of the five nucleosides that make up DNA and RNA is its primary role, but there are many other benefits to uridine.
Uridine is also a cognitive enhancer and is especially powerful when taken with DHA and choline to improve memory and learning.
The combination of these three nutrients can help increase the number of synapses formed in the brain, which increases your brain’s neuroplasticity.
Plasticity does not increase immediately, but after a few continuous days of use.
Uridine, when used with choline, has been shown to significantly increase alertness and focus. It also improves mood as it increases the production and release of dopamine, sometimes referred to as “the motivation molecule.”
This can also lead to an improved mood and lessen the effects of depression.
Taking uridine with vitamin B12 and folic acid has been shown to decrease the amount of inflammation in the body.
It has been used as a treatment against the pain associated with carpal tunnel and relieve some of the symptoms associated with gout and arthritis.
Uridine is well-tolerated and safe at a daily dose of 500-1,000mg per day. Some forums report better effects at 1,000-2,000mg per day, but dosages at that level can create stomach discomfort.
The benefits of uridine are also improved when supplementing with other nutrients, such as choline, DHA, folic acid or vitamin B12.
Uridine monophosphate is available in capsule or powdered form. It is water-soluble, so it can be easily mixed in a glass of water, fruit juice or other beverage.
Uridine has few reported side effects when taken at normal doses. Some side effects may occur at higher doses but generally disappear when the dosage is reduced.
These side effects include: vomiting, nausea, and diarrhea.
While uridine can provide benefits when taken by itself, this nootropic really shines when stacked with other nootropics.
To enhance cognitive functions, try a popular stack that is known online as the “Mr. Happy Stack.”
That is a stack consisting of uridine, DHA (fish oil) and choline. Instructions say to take 150-250mg of uridine monophosphate, one dose of fish oil and a multivitamin twice a day for two weeks.
After the first two weeks, start adding in 50mg of Alpha GPC or CDP choline and slowly build up to 300mg. ALCAR may be substituted for choline if you experience any side effects from choline.
To reduce inflammation in the body, try a stack with 150-250mg of uridine monophosphate and a dose of folic acid and vitamin B12 twice a day.
Overview of Uridine nootropic
Uridine is necessary for all life as it one of the nucleoside that make up RNA, but it also has a strong positive effect on your brain’s health.
Uridine could be one of the most important supplements we’ve never heard of!
To keep your brain healthy as you age, it would be highly recommended starting a daily dose of uridine, fish oil (DHA) and choline.