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Benefits and Effects of Sulbutiamine Supplement for Cognitive Enhancement

Benefits and Effects of Sulbutiamine Supplement for Cognitive Enhancement

What is Sulbutiamine Nootropic Supplement

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Sulbutiamine is derived from vitamin B1, thiamine. It was discovered in Japan in the 1950’s when scientists were looking to create a more bioavailable form of thiamine.

It was marketed in France in the 1970’s under the name Arcalion as a treatment for fatigue, but was later discontinued due to lack of supporting data.

However, some endurance athletes still use sulbutiamine as a performance enhancer.

Benefits and Effects of Sulbutiamine Supplement for Cognitive Enhancement

Benefits and Effects Sulbutiamine Supplement for Cognitive Enhancement

Sulbutiamine is a synthetically enhanced version of thiamine, which is an important vitamin for the brain’s ability to regulate acetylcholine levels. Unlike thiamine, which is water soluble, sulbutiamine is fat soluble and can easily pass the blood-brain barrier.

The main benefits of sulbutiamine are increased energy and memory. If you’re feeling low on energy, then sulbutiamine may be able to provide you the boost you need. However, as a nootropic, it’s sulbutiamine’s ability to boost memory that is significant.

A lack of vitamin B1 in the body can lead to problems with memory, attention span and mood. A deficiency in vitamin B1 can lower energy levels and then coupled with a lack of exercise can lead to profound depression.

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Since vitamin B1 s an important component in your body’s ability to regulate acetylcholine, a neurotransmitter, it makes sense that sulbutiamine is able to enhance memory and mood.


Sulbutiamine is available in capsule or powdered form, but the powdered form tastes terrible. It is fat soluble, so it’s best taken with food or mixed with an oil. The recommended dosage is 200-800mg per day. A dose of 400mg in the morning is typical.

It’s also easy to build a tolerance to sulbutiamine, so it’s not recommended taking it on a daily basis for more than a few days or to exceed the recommended dose as some users report anxiety as a side effect. It’s better to develop a cycle, three days on and one day off, for example. Even better would be to just take on occasion when an additional boost is needed.

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Side Effects

Sulbutiamine has very few side effects when taken at normal doses. These side effects could include headache, nausea, and trouble sleeping. Users experimenting with doses higher than normal have reported anxiety and negative thoughts.


Sulbutiamine works well on its own for an occasional boost to energy or mood, but can be stacked with other nootropics to maximize effects.

Sulbutiamine stacks well with racetams, but especially aniracetam. Try stacking 400mg sulbutiamine, 800mg aniracetam and 300mg GPC Choline once or twice a day.

Sulbutiamine stacks well with aniracetam, piracetam, pramiracetam and Alpha GPC or CDP choline.

Overview of The Cognitive Enhancer Sulbutiamine Supplement

Sulbutiamine is a great nootropic to take for an occasional boost of energy when studying or for physical training but should not be taken on a regular basis.

It’s great for an extra boost of energy, but it also provides a great boost for memory as well.

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